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Institut für Medizinische Mikrobiologie

Alisa Garaeva

Dr. Alisa Garaeva

  • Postdoctoral Research Assistant
+41 44 634 27 99

Curriculum vitae

working experience
2016-2021 PhD student, University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute, Membrane Enzymology, Groningen, the Netherlands (Prof. D.J. Slotboom, Prof. C. Paulino, Prof. A. Guskov)
2019 EMBO short-term fellowship, Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland (Prof. M.A. Seeger)
2010-2015 Specialist (BSci+MSci) in bioengineering and bioinformatics, Moscow State University, Moscow, Russia


Student intern in Laboratory of Molecular Biology of the Gene, Belozersky Institute of Physico-Chemical Biology, Moscow, Russia


Summer school in bioinformatics, Department of Microbiology, Leiden University Medical Center, Leiden, the Netherlands


Cyril and Methodius Lyceum, focus on Chemistry and Biology, Smolensk, Russia

Research interests

  • Iron transport in Mycobacteria
  • Structure and function of membrane transport proteins
  • Single particle cryo-EM


Cryo-EM structure of the human neutral amino acid transporter ASCT2.
Garaeva AA, Oostergetel GT, Gati C, Guskov A, Paulino C, Slotboom DJ (2018)
Nat Struct Mol Biol 25: 515-521

Elevator-type mechanisms of membrane transport.
Garaeva AA, Slotboom DJ (2020)
Biochem Soc Trans 48: 1227-1241

A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2.
Garaeva AA, Guskov A, Slotboom DJ, Paulino C (2019)
Nat Commun 10: 3427

PnuT uses a facilitated diffusion mechanism for thiamine uptake.
Jaehme M, Singh R, Garaeva AA, Duurkens RH, Slotboom DJ (2018)
J Gen Physiol 150: 41-50

Mitochondrial dysfunction induces SESN2 gene expression through Activating Transcription Factor 4.
Garaeva AA, Kovaleva IE, Chumakov PM, Evstafieva AG (2016)
Cell Cycle 15: 64-71

Intermedin/adrenomedullin 2 is a stress-inducible gene controlled by activating transcription factor 4.
Kovaleva IE, Garaeva AA, Chumakov PM, Evstafieva AG (2016)
Gene 590: 177-85

A sustained deficiency of mitochondrial respiratory complex III induces an apoptotic cell death through the p53-mediated inhibition of pro-survival activities of the activating transcription factor 4.
Evstafieva AG, Garaeva AA, Khutornenko AA, Klepikova AV, Logacheva MD, Penin AA, Novakovsky GE, Kovaleva IE, Chumakov PM (2014)
Cell Death Dis 5: e1511