Michaela   Oborská

Michaela Oborská

PhD Student

Tel.: +41 44 634 5318

moplova@imm.uzh.ch

Webseite

Education

2016-present Doctoral studies in RNA biology (Prof. V. G. Panse)
2015 Research Internship at Aarhus University, Denmark (Prof. T. H. Jensen)
2013-2015 Master of Science in Cell and Developmental biology, Charles University in Prague
2013-2014 Erasmus exchange programme, University of Copenhagen, Denmark (Prof. P. Brodersen)
2010-2013 Bachelor of Science in Molecular Biology and Biochemistry of the Organisms, Charles University in Prague
2002-2010 Church Grammar School Plzeň

 

Research interest

  • Cell Physiology
  • Ribosome assembly pathway and its quality control mechanisms
  • Evolution of the ribosome biogenesis

Awards

2017 Boehringer Ingelheim Fonds (BIF) PhD fellowship

Publications

High-throughput functional characterization of protein phosphorylation sites in yeast.
Viéitez C, Busby BP, Ochoa D, Mateus A, Memon D, Galardini M, Yildiz U, Trovato M, Jawed A, Geiger AG, Oborská-Oplová M, Potel CM, Vonesch SC, Szu Tu C, Shahraz M, Stein F, Steinmetz LM, Panse VG, Noh KM, Savitski MM, Typas A, Beltrao P (2021)
Nat Biotechnol: Online ahead of print

Puf6 primes 60S pre-ribosome nuclear export at low temperature.
Gerhardy S, Oborská-Oplová M, Gillet L, Börner R, van Nues R, Leitner A, Michel E, Petkowski JJ, Granneman S, Sigel RKO, Aebersold R, Panse VG (2021)
Nat Commun 12: 4696

Mapping domains of ARS2 critical for its RNA decay capacity.
Melko M, Winczura K, Rouvière JO, Oborská-Oplová M, Andersen PK, Jensen TH (2020)
Nucleic Acids Res 48: 6943–6953

The ribotoxin α-sarcin can cleave the sarcin/ricin loop on late 60S pre-ribosomes.
Olombrada M, Peña C, Rodríguez-Galán O, Klingauf-Nerurkar P, Portugal-Calisto D, Oborská-Oplová M, Altvater M, Gavilanes JG, Martínez-Del-Pozo Á, de la Cruz J, García-Ortega L, Panse VG (2020)
Nucleic Acids Res: Online ahead of print

The GTPase Nog1 co-ordinates assembly, maturation and quality control of distant ribosomal functional centers.
Klingauf-Nerurkar P, Gillet LC, Portugal-Calisto D, Oplova M, Jäger M, Schubert OT, Pisano A, Peña C, Rao S, Altvater M, Chang Y, Aebersold R, Panse VG (2020)
Elife 9: e52474

Conserved phosphorylation hotspots in eukaryotic protein domain families.
Strumillo MJ, Oplová M, Viéitez C, Ochoa D, Shahraz M, Busby BP, Sopko R, Studer RA, Perrimon N, Panse VG, Beltrao P.(2019)
Nat Commun 10: 1977

Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2.
Schütz S, Michel E, Damberger FF, Oplová M, Peña C, Leitner A, Aebersold R, Allain FH, Panse VG (2018)
Nat Commun 9: 3669