Dr. Justin Walter

Dr. Justin Walter

Postdoctoral Research Assistant

Tel.: +41 44 634 27 99

jwalter@imm.uzh.ch

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Curriculum vitae

Education and working experience

2014-2019

PhD Research, Department of Biochemistry, University of Zurich (Prof. R. Dutzler)

2010-2013

Research Technologist, Department of Chemistry, Western Washington University, Bellingham, WA, USA (Prof. P. Clint Spiegel)

2008-2010

Master of Science, Department of Chemistry, Western Washington University, Bellingham, WA, USA (Prof. P. Clint Spiegel)

2002-2007

Bachelor of Science, Biochemistry, Western Washington University, Bellingham WA, USA

1998-2002

Woodrow Wilson High School, Tacoma, WA, USA

 
 

Research Interests

  • Application of NestLink technology for in vivo binder targeting
  • Engineering protein shuttles to deliver cargo across the mammalian blood-brain barrier
  • Structure and function of membrane transport proteins

Publications

Cryo-EM structures and functional characterization of murine Slc26a9 reveal mechanism of uncoupled chloride transport.
Walter JD, Sawicka M, Dutzler R (2019)
Elife 8: e46986

Ribosomal protein L7/L12 is required for GTP ase translation factors EF‐G, RF 3, and IF 2 to bind in their GTP state to 70S ribosomes.
Carlson MA, Haddad BG, Weis AJ, Blackwood CS, Shelton CD, Wuerth ME, Walter JD, Spiegel Jr PC (2017)
FEBS J 284: 1631-43

The 1.7 Å X-ray crystal structure of the porcine factor VIII C2 domain and binding analysis to anti-human C2 domain antibodies and phospholipid surfaces
Brison CM, Mullen SM, Wuerth ME, Podolsky K, Cook M, Herman JA, Walter JD, Meeks SL, Spiegel PC (2015)
PloS one 10: e0122447

Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopes
Walter JD, Werther RA, Brison CM, Cragerud RK, Healey JF, Meeks SL, Lollar P, Spiegel PC (2013)
Blood 122: 4270-4278

Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies
Walter JD, Werther RA, Polozova MS, Pohlman J, Healey JF, Meeks SL, Lollar P, Spiegel PC (2013)
J Biol Chem 288: 9905-9914

Thiostrepton inhibits stable 70S ribosome binding and ribosome-dependent GTPase activation of elongation factor G and elongation factor 4
Walter JD, Hunter M, Cobb M, Traeger G, Spiegel PC (2011)
Nucleic acids Res 40: 360-370

Expression, purification, and analysis of unknown translation factors from Escherichia coli: A synthesis approach
Walter JD, Littlefield P, Delbecq S, Prody G, Spiegel PC (2010)
Biochem Mol Biol Educ 38: 17-22